Articles

Trajectories of objectively measured physical activity and mood states in older Japanese adults: longitudinal data from the Nakanojo Study

Japan, like many developed countries, now faces fiscal problems from the escalating health-care expenditures associated with an aging population. Mental health problems such as depression contribute as much to...

Authors: Shuji Inada, Kazuhiro Yoshiuchi, Sungjin Park and Yukitoshi Aoyagi

Factors influencing post-ICU psychological distress in family members of critically ill patients: a linear mixed-effects model

Adverse responses to critical illness, such as symptoms of depression, anxiety or posttraumatic stress, are relatively common among family members. The role of risk factors, however, remains insufficiently und...

Authors: Rahel Naef, Stefanie von Felten and Jutta Ernst

A randomized, double-blind, placebo-controlled study to assess efficacy of mirtazapine for the treatment of diarrhea predominant irritable bowel syndrome

Ample evidence indicates the efficacy of serotonin type 3 (5-HT₃) receptor antagonists in the treatment of patients with diarrhea-predominant irritable bowel syndrome (IBS-D). Mirtazapine is an atypical antidepre...

Authors: Alireza Khalilian, Davoud Ahmadimoghaddam, Shiva Saki, Younes Mohammadi and Maryam Mehrpooya

Eye gaze differences in school scenes between preschool children and adolescents with high-functioning autism spectrum disorder and those with typical development

Children with autism spectrum disorder (ASD) may experience difficulty adapting to daily life in a preschool or school settings and are likely to develop psychosomatic symptoms. For a better understanding of t...

Authors: Yuko Ishizaki, Takahiro Higuchi, Yoshitoki Yanagimoto, Hodaka Kobayashi, Atsushi Noritake, Kae Nakamura and Kazunari Kaneko

The psychosocial barriers to medication adherence of patients with type 2 diabetes: a qualitative study

The adherence of diabetic patients to their medication regimen is associated with many psychosocial factors that are still unknown. Therefore, the present study aims to identify the psychosocial barriers to me...

Authors: Firoozeh Mostafavi, Fereshteh Zamani Alavijeh, Arash Salahshouri and Behzad Mahaki

Biopsychosocial medicine research trends: connecting clinical medicine, psychology, and public health

Authors: Mutsuhiro Nakao, Gen Komaki, Kazuhiro Yoshiuchi, Hans-Christian Deter and Shin Fukudo

The psychosocial profile of family caregivers of children with chronic diseases: a cross-sectional study

A family caregiver is defined as a person who has a significant emotional bond with the patient; this caregiver is a family member who is a part of the patient’s family life cycle; offers emotional-expressive,...

Authors: Filiberto Toledano-Toledano and David Luna

Personality traits mediate the association between perceived parental bonding and well-being in adult volunteers from the community

Previous studies reported that subjective well-being in adulthood correlates with perceived parental bonding in childhood as well as personality traits. However, whether personality traits mediate the effect o...

Authors: Akiko Murakoshi, Nobuyuki Mitsui, Jiro Masuya, Yota Fujimura, Shinji Higashi, Ichiro Kusumi and Takeshi Inoue

Educational supportive group therapy and the quality of life of hemodialysis patients

In addition to physical, mental, and social condition, ESRD and hemodialysis affect the quality of life of patients as well. Psychotherapy and non-pharmaceutical interventions are effective measures to add mea...

Authors: Sajad Mansouri, Amir Jalali, Mahmoud Rahmati and Nader Salari

Personal values in adolescence and their associations with metabolic biomarkers in adulthood: a Japanese population-based study

Personal values, which are formed in early life, can have an impact on health outcome later in life.

Authors: Natsu Sasaki, Kazuhiro Watanabe and Norito Kawakami

Association between polypharmacy and the persistence of delirium: a retrospective cohort study

Although the association between polypharmacy and the occurrence of delirium has been well studied, the influence of polypharmacy on the persistence of delirium remains unclear. We aimed to explore the effect ...

Authors: Ken Kurisu, Daisuke Miyabe, Yoshiko Furukawa, Osamu Shibayama and Kazuhiro Yoshiuchi

Higher galectin-3 levels are independently associated with lower anxiety in patients with risk factors for heart failure

Galectin-3 promotes the proliferation of neural progenitor cells and is engaged in cell-cell adhesion, cell-matrix interactions, and macrophage activation. In addition, in patients with heart failure this carb...

Authors: Monika Sadlonova, Thomas Meyer, Lutz Binder, Rolf Wachter, Frank Edelmann and Christoph Herrmann-Lingen

Shitsu-taikan-sho (alexisomia): a historical review and its clinical importance

“Shitsu-taikan-sho” is a clinical concept that refers to characteristics of having difficulty in the awareness and expression of somatic feelings or sensations. This concept was first proposed in 1979 by Dr. Y...

Authors: Takakazu Oka

The prognosis and prevention measures for mental health in COVID-19 patients: through the experience of SARS

Due to the high pathogenicity and mortality, the COVID-19 disaster caused global panic and anxiety. At present, diagnosis and treatment are of great concern. As time progresses, however, the sequelae caused by...

Authors: Guo Heng Mo, Zi Xuan Wang, Xiao Si Chen and Qunguang Jiang

Alexithymia 3.0: reimagining alexithymia from a medical perspective

Although alexithymia research has greatly expanded in recent decades, our ability to treat it clinically remains limited. This article provides a new perspective on why that may be true and offers a fresh appr...

Authors: Richard D. Lane

Affective agnosia: a core affective processing deficit in the alexithymia spectrum

Affective agnosia, an impairment in knowing how one feels emotionally, has been described as an extreme deficit in the experience and expression of emotion that may confer heightened risk for adverse medical o...

Authors: Richard D. Lane, Mark Solms, Karen L. Weihs, Alex Hishaw and Ryan Smith

Development of a new Japanese version of the Clinical Impairment Assessment Questionnaire

The Clinical Impairment Assessment questionnaire (CIA) is used to measure the severity of psychosocial impairment in patients with eating disorders. The purpose of the present study was to develop a new Japane...

Authors: Takeshi Horie, Maiko Hiraide, Shu Takakura, Tomokazu Hata, Nobuyuki Sudo and Kazuhiro Yoshiuchi

Correction to: Very long chain fatty acids are an important marker of nutritional status in patients with anorexia nervosa: a case control study

An amendment to this paper has been published and can be accessed via the original article.

Authors: Miki Shimizu, Keisuke Kawai, Makoto Yamashita, Masayasu Shoji, Shu Takakura, Tomokazu Hata, Megumi Nakashima, Keita Tatsushima, Kazunari Tanaka and Nobuyuki Sudo

The association of depression, loneliness and internet addiction levels in patients with acne vulgaris

Acne vulgaris is a very common skin disorder that has negative effects on the mood, self image and social relations of the patients. We want to evaluate the effects of acne vulgaris and its severity on depress...

Authors: Coşkun Öztekin and Aynure Öztekin

Reliability and validity of the Japanese translation of the Eating Disorders Quality of Life (ED-QOL) scale for Japanese healthy female university undergraduate students and patients with eating disorders

The Eating Disorder Quality of Life (ED-QOL) scale is a 25-item self-report measure that assesses health-related quality of life (HRQoL) of eating-disorder patients. Although the ED-QOL is one of the most wide...

Authors: Ryo Yoneda, Makoto Otani, Maiko Hiraide, Takeshi Horie, Tomoyo Mitsui, Toshiyuki Yoshida, Gen Komaki and Kazuhiro Yoshiuchi

The accuracy of delirium assessment by cardiologists treating heart failure inpatients: a single center retrospective survey

Patients with heart failure (HF) accompanied by delirium are at risk of rehospitalization and death, thus early detection and appropriate treatment is imperative. Palliative care for patients with HF is an imp...

Authors: Anna Hayashi, Sayaka Kobayashi, Kentaro Matsui, Rie Akaho and Katsuji Nishimura

Very long chain fatty acids are an important marker of nutritional status in patients with anorexia nervosa: a case control study

Anorexia nervosa (AN) is a disease resulting in extreme weight loss. It is caused by multiple factors, including psychosocial, environmental, and genetic factors. A genetic abnormality affecting lipid metaboli...

Authors: Miki Shimizu, Keisuke Kawai, Makoto Yamashita, Masayasu Shoji, Shu Takakura, Tomokazu Hata, Megumi Nakashima, Keita Tatsushima, Kazunari Tanaka and Nobuyuki Sudo

Effect of relaxation therapy on benzodiazepine use in patients with medically unexplained symptoms

The change in the benzodiazepine (BZD) use of patients with medically unexplained symptoms (MUS) following the application of relaxation therapy were examined.

Authors: Kazuaki Hashimoto, Takeaki Takeuchi, Akiko Koyama, Miki Hiiragi, Shunsuke Suka and Masahiro Hashizume

Physical activity and disability in patients with noncardiac chest pain: a longitudinal cohort study

Noncardiac chest pain (NCCP) is one of the leading reasons for emergency department visits and significantly limits patients’ daily functioning. The protective effect of physical activity has been established ...

Authors: Joanne Castonguay, Stéphane Turcotte, Richard P Fleet, Patrick M Archambault, Clermont E Dionne, Isabelle Denis and Guillaume Foldes-Busque

The effects of usual Care in Psychosocial Intervention Trials of patients with coronary artery disease: a systematic review

Many intervention studies of coronary artery disease (CAD) have found health benefits for patients in the “treatment as usual” (TAU) group like in the specific psychotherapy group. In this pilot study, we want...

Authors: Hans-Christian Deter and Kristina Orth-Gomér

Associations between the depressive symptoms, subjective cognitive function, and presenteeism of Japanese adult workers: a cross-sectional survey study

Presenteeism has attracted much attention in the research into mental health. However, how cognitive complaints and depressive symptoms affect presenteeism remains unknown. Therefore, this study examined the c...

Authors: Kuniyoshi Toyoshima, Takeshi Inoue, Akiyoshi Shimura, Jiro Masuya, Masahiko Ichiki, Yota Fujimura and Ichiro Kusumi

Post-traumatic stress symptoms in hemodialysis patients with MERS-CoV exposure

Post-traumatic stress symptoms can occur in patients with medical illness. During the Middle East Respiratory Syndrome (MERS) outbreak in South Korea in 2015, some dialysis patients in three centers who were i...

Authors: A Jin Cho, Hong-Seock Lee, Young-Ki Lee, Hee Jung Jeon, Hayne Cho Park, Da-Wun Jeong, Yang-Gyun Kim, Sang-Ho Lee, Chang-Hee Lee, Kyung Don Yoo and Ae Kyeong Wong

Iron deficiency anemia, stunted growth, and developmental delay due to avoidant/restrictive food intake disorder by restricted eating in autism spectrum disorder

Authors: Yoshitoki Yanagimoto, Yuko Ishizaki and Kazunari Kaneko

Effects of interoceptive training on decision making, anxiety, and somatic symptoms

Interoception is the perception of afferent information that arises from any point within the body. Individual differences in interoception have been associated with affective processing and decision-making pr...

Authors: Ayako Sugawara, Yuri Terasawa, Ruri Katsunuma and Atsushi Sekiguchi

Pilot study of a basic individualized cognitive behavioral therapy program for chronic pain in Japan

Chronic pain is a major health problem, and cognitive behavioral therapy (CBT) is its recommended treatment; however, efforts to develop CBT programs for chronic pain and assess their feasibility are remarkabl...

Authors: Hiroki Hosogoshi, Kazunori Iwasa, Takaki Fukumori, Yuriko Takagishi, Yoshitake Takebayashi, Tomonori Adachi, Yuki Oe, Yukino Tairako, Yumiko Takao, Hiroyuki Nishie, Ayako Kanie, Masaki Kitahara, Kiyoka Enomoto, Hirono Ishii, Issei Shinmei, Masaru Horikoshi…

Personalized cognitive-behavioural therapy for obesity (CBT-OB): theory, strategies and procedures

Personalized cognitive-behavioural therapy for obesity (CBT-OB) is a new treatment that combines the traditional procedures of standard behavioural therapy for obesity (i.e., self-monitoring, goal setting, sti...

Authors: Riccardo Dalle Grave, Massimiliano Sartirana and Simona Calugi

“Phantom akathisia” in an amputated leg of a sarcoma patient: a case report

Akathisia is a rather common extrapyramidal side effect of antipsychotic drugs and antidepressants, often resulting in severe discomfort for patients. However, due to the diversity of symptoms, it is often ove...

Authors: Mayumi Ishida, Jungo Imanishi, Yasuo Yazawa, Yu Sunakawa, Tomoaki Torigoe and Hideki Onishi

Effectiveness of enhanced cognitive behavior therapy for bulimia nervosa in Japan: a randomized controlled trial protocol

The effectiveness of psychotherapeutic interventions for eating disorders (EDs) is widely studied in Europe, North America, and Australia/New Zealand. However, few controlled studies and no randomized controll...

Authors: Chisato Ohara, Atsushi Sekiguchi, Shu Takakura, Yuka Endo, Naho Tamura, Hiroe Kikuchi, Kazushi Maruo, Norio Sugawara, Kenji Hatano, Hitomi Kawanishi, Misako Funaba, Ayako Sugawara, Nobuhiro Nohara, Keisuke Kawai, Shin Fukudo, Nobuyuki Sudo…

The relation between mindfulness and the fatigue of women with breast cancer: path analysis

Although fatigue is a common and distressing symptom in cancer survivors, the mechanism of fatigue is not fully understood. Therefore, this study aims to investigate the relation between the fatigue and mindfu...

Authors: Kaori Ikeuchi, Hiroshi Ishiguro, Yasunori Nakamura, Tomoko Izawa, Nobuhiko Shinkura and Kazuko Nin

Physical and psychological aspects of anorexia nervosa based on duration of illness: a cross-sectional study

We evaluated physical and psychological features of patients with anorexia nervosa (AN) who differed by duration of illness.

Authors: Shu Takakura, Chie Suzuyama Aso, Kenta Toda, Tomokazu Hata, Makoto Yamashita and Nobuyuki Sudo

Improvement in oral health related quality of life among the elderly: a randomized controlled trial

The present study was conducted to determine the impact of educational intervention based on adult learning theory on oral health related quality of life of the elderly.

Authors: Elham Shokouhi, Hashem Mohamadian, Fatemeh Babadi, Bahman Cheraghian and Marzieh Araban

Changes in circulating microRNA after recumbent isometric yoga practice by patients with myalgic encephalomyelitis/chronic fatigue syndrome: an explorative pilot study

Yoga is a representative mind-body therapy. Our previous studies have demonstrated that isometric yoga (i.e. yoga programs that we developed so individuals can practice yoga poses with a self-adjustable isomet...

Authors: Shu Takakura, Takakazu Oka and Nobuyuki Sudo

Hemodynamic response to familiar faces in children with ADHD

School-age children with attention deficit hyperactivity disorder (ADHD) have difficulties in interpersonal relationships, in addition to impaired facial expression perception and recognition. For successful s...

Authors: Keiichi Shimamura, Takeshi Inoue, Hiroko Ichikawa, Emi Nakato, Yuiko Sakuta, So Kanazawa, Masami K. Yamaguchi, Ryusuke Kakigi and Ryoichi Sakuta

The relationship between dietary inflammatory index and psychosomatic complaints profiles: results from SEPAHAN cross-sectional study

Although the dietary inflammatory index (DII) has been evaluated in relation to psychological disorders risk, the association between DII and psychosomatic complaints is unclear. This study aimed to determine ...

Authors: Fahimeh Haghighatdoost, Awat Feizi, Ahmad Esmaillzadeh, Christine Feinle-Bisset, Ammar Hassanzadeh Keshteli, Hamidreza Roohafza, Hamid Afshar and Peyman Adibi

The longitudinal effects of seated isometric yoga on blood biomarkers, autonomic functions, and psychological parameters of patients with chronic fatigue syndrome: a pilot study

In a previous randomized controlled trial, we found that practicing seated isometric yoga regularly for 2 months improved the fatigue of patients with chronic fatigue syndrome (CFS) who are resistant to conven...

Authors: Takakazu Oka, Tokusei Tanahashi, Battuvshin Lkhagvasuren and Yu Yamada

A potential relation between premenstrual symptoms and subjective perception of health and stress among college students: a cross-sectional study

A majority of women from all cultures and socioeconomic levels experience myriad symptoms known as premenstrual syndrome during the days prior to menstruation. The present study investigated commonly reported ...

Authors: Tamaki Matsumoto, Miho Egawa, Tetsuya Kimura and Tatsuya Hayashi

Weight loss in conservative treatment of obesity in women is associated with physical activity and circadian phenotype: a longitudinal observational study

The study investigates the association between circadian phenotype (CP), its stability (interdaily stability - IS) and physical activity (PA) in a weight loss (WL) programme.

Authors: Eva Fárková, Jakub Schneider, Michal Šmotek, Eduard Bakštein, Jitka Herlesová, Jana Kopřivová, Petra Šrámková, Dita Pichlerová and Martin Fried

Effects of reflexology on premenstrual syndrome: a systematic review and meta-analysis

Premenstrual syndrome (PMS) refers to a set of somatic and psychological symptoms that occur cyclically in the luteal phase of a menstrual cycle. There is no report of final result of reflexology on PMS. There...

Authors: Marzieh Hasanpour, Mohammad Mehdi Mohammadi and Habib Shareinia

Controlling the laxative abuse of anorexia nervosa patients with the Serigaya Methamphetamine Relapse Prevention Program workbook: a case report

There is no consensus on effective treatment for laxative abuse in patients with eating disorders. Here, we report the case of a patient with laxative abuse who showed some improvement through an intervention ...

Authors: Kuniyoshi Toyoshima and Ichiro Kusumi

The effectiveness of intervention with board games: a systematic review

To examine the effectiveness of board games and programs that use board games, the present study conducted a systematic review using the PsycINFO and PubMed databases with the keywords “board game” AND “trial;...

Authors: Shota Noda, Kentaro Shirotsuki and Mutsuhiro Nakao

Validation of a childhood eating disorder outcome scale

We developed and validated a childhood eating disorder outcome scale based on outcomes associated with body mass index standard deviation score (BMI-SDS). This prospective observational study included 131 chil...

Authors: Shinichiro Nagamitsu, Yoshimitsu Fukai, So Uchida, Michiko Matsuoka, Toshiyuki Iguchi, Ayumi Okada, Ryoichi Sakuta, Takeshi Inoue, Ryoko Otani, Shinji Kitayama, Kenshi Koyanagi, Yuichi Suzuki, Yuki Suzuki, Yoshino Sumi, Shizuo Takamiya, Chikako Fujii…

Preceding psychological factors and calorie intake in patients with type 2 diabetes: investigation by ecological momentary assessment

Psychological factors have been reported to have influence on the eating habits of patients with diabetes. However, previous studies have used questionnaires to investigate the association, and thus include re...

Authors: Shuji Inada, Yoko Iizuka, Ken Ohashi, Hiroe Kikuchi, Yoshiharu Yamamoto, Takashi Kadowaki and Kazuhiro Yoshiuchi

Potential benefits of integrating ecological momentary assessment data into mHealth care systems

The advancement of wearable/ambulatory technologies has brought a huge change to data collection frameworks in recent decades. Mobile health (mHealth) care platforms, which utilize ambulatory devices to collec...

Authors: Jinhyuk Kim, David Marcusson-Clavertz, Kazuhiro Yoshiuchi and Joshua M. Smyth

Iron deficiency anemia induced by magnesium overuse: a case report

Although in vitro studies show that iron absorption can be inhibited by magnesium laxatives such as magnesium oxide, taking oral iron supplements with magnesium laxatives is not considered a clinical problem.

Authors: Hiroshi Sugimoto and Ui Yamada

Developing a Japanese version of the Injustice Experience Questionnaire-chronic and the contribution of perceived injustice to severity of menstrual pain: a web-based cross-sectional study

Menstrual pain causes low quality of life among women of reproductive age, and often interferes with daily activities. Perceived injustice is a cognition linked to adverse symptoms. The aims of this study were...

Authors: Keiko Yamada, Tomonori Adachi, Yasuhiko Kubota, Takashi Takeda and Masako Iseki