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  1. Research

    Randomized, placebo-controlled, phase IV pilot study of ramosetron to evaluate the co-primary end points in male patients with irritable bowel syndrome with diarrhea

    Global assessment allows patients to assess improvement in multiple irritable bowel syndrome (IBS) symptoms. However, it was deemed important to assess “clinically meaningful improvements, focusing on the pati...

    Motoko Ida, Akito Nishida, Hiraku Akiho, Yoshihiro Nakashima, Kei Matsueda and Shin Fukudo

    BioPsychoSocial Medicine 2017 11:8

    Published on: 16 March 2017

  2. Research

    Evaluation of the irritable bowel syndrome severity index in Japanese male patients with irritable bowel syndrome with diarrhea

    Previous studies have indicated that ramosetron, a 5-hydroxytryptamine-3 receptor antagonist, achieves global improvement in irritable bowel syndrome (IBS) symptoms in male patients with IBS with diarrhea (IBS...

    Motoko Ida, Akito Nishida, Hiraku Akiho, Yoshihiro Nakashima, Kei Matsueda and Shin Fukudo

    BioPsychoSocial Medicine 2017 11:7

    Published on: 11 March 2017

  3. Research

    Development of a recumbent isometric yoga program for patients with severe chronic fatigue syndrome/myalgic encephalomyelitis: A pilot study to assess feasibility and efficacy

    Our previous randomized controlled trial demonstrated that isometric yoga in a sitting position reduces fatigue in patients with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). However, some patie...

    Takakazu Oka, Hisako Wakita and Keishin Kimura

    BioPsychoSocial Medicine 2017 11:5

    Published on: 3 March 2017

  4. Research

    Job crafting, work engagement, and psychological distress among Japanese employees: a cross-sectional study

    Job crafting, an employee-initiated job design/redesign, has become important for employees’ well-being. However, most studies on the relationship between job crafting and employees’ well-being have been condu...

    Asuka Sakuraya, Akihito Shimazu, Hisashi Eguchi, Kimika Kamiyama, Yujiro Hara, Katsuyuki Namba and Norito Kawakami

    BioPsychoSocial Medicine 2017 11:6

    Published on: 10 February 2017

  5. Research

    Tolerable pain reduces gastric fundal accommodation and gastric motility in healthy subjects: a crossover ultrasonographic study

    Obstacles to pain management include patients’ reluctance to inform healthcare provides about their pain, and differences in the pain management aims between patients and healthcare providers. The objective of...

    Hideaki Hasuo, Hiroaki Kusunoki, Kenji Kanbara, Tetsuya Abe, Naoko Yunoki, Ken Haruma and Mikihiko Fukunaga

    BioPsychoSocial Medicine 2017 11:4

    Published on: 1 February 2017

  6. Case report

    A series of patients with purging type anorexia nervosa who do “tube vomiting”

    It is important for clinicians to assess their patients’ purging behavior. Various methods of purging, such as self-induced vomiting are well-known. Because patients do not always report their purging behavior...

    Takeshi Horie, Saki Harashima, Ryo Yoneda, Maiko Hiraide, Shuji Inada, Makoto Otani and Kazuhiro Yoshiuchi

    BioPsychoSocial Medicine 2016 10:32

    Published on: 15 November 2016

  7. Research

    What inhibits working women with mental disorders from returning to their workplace?-A study of systematic re-employment support in a medical institution

    It has been customary for working women in Japan to retire when they marry and to devote themselves to household work as well as having children. However, according to a report published by the Ministry of Int...

    Karin Hayashi, Yoichi Taira, Takamitsu Maeda, Yumie Matsuda, Yuki Kato, Kozue Hashi, Nobuo Kuroki and Shuichi Katsuragawa

    BioPsychoSocial Medicine 2016 10:29

    Published on: 18 October 2016

  8. Research

    Factors associated with pain level in non-cardiac chest pain patients with comorbid panic disorder

    Panic disorder (PD) is highly prevalent in patients with non-cardiac chest pain (NCCP). This study aims to explore the role of psychological factors (PD intensity, anxiety sensitivity, heart-related fear, atte...

    Guillaume Foldes-Busque, Stéphanie Hamel, Geneviève Belleville, Richard Fleet, Julien Poitras, Jean-Marc Chauny, Alain Vadeboncoeur, Kim L. Lavoie and André Marchand

    BioPsychoSocial Medicine 2016 10:30

    Published on: 18 October 2016

  9. Research

    A questionnaire survey regarding the support needed by Yogo teachers to take care of students suspected of having eating disorders (second report)

    The lowering of the age of onset and chronicity have been key problems related to eating disorders (EDs). As the proportion of teens in the estimated onset ages has increased, it has become important to detect...

    Kaoru Seike, Michiko Nakazato, Hisashi Hanazawa, Toshiyuki Ohtani, Tomihisa Niitsu, Shin-ichi Ishikawa, Atsuko Ayabe, Ryoko Otani, Kentaro Kawabe, Fumie Horiuchi, Shizuo Takamiya and Ryoichi Sakuta

    BioPsychoSocial Medicine 2016 10:28

    Published on: 29 September 2016

  10. Case report

    Self-controllable prodromal symptoms of syncope attributed to carotid sinus syndrome during the end stage of cancer: a case report

    Carotid sinus syndrome (CSS) can cause prodromal symptoms of syncope such as dizziness and nausea. Patients with end-stage cancer lose self-efficacy associated with reduced activities of daily life (ADL). Here...

    Hideaki Hasuo, Kenji Kanbara, Hiroko Sakuma, Rie Matsumori and Mikihiko Fukunaga

    BioPsychoSocial Medicine 2016 10:27

    Published on: 5 September 2016

  11. Research

    Inhibition of emotional needs and emotional wellbeing predict disease progression of chronic hepatitis C patients: an 8-year prospective study

    The role of psycosocial factors in the disease progression of chronic hepatitis C (CHC) patients remains unclear. The aim of the present study was to prospectively evaluate the prognostic value of behavioral p...

    Ryoko Sawamoto, Jun Nagano, Eiji Kajiwara, Junko Sonoda, Tetsuya Hiramoto and Nobuyuki Sudo

    BioPsychoSocial Medicine 2016 10:24

    Published on: 29 July 2016

  12. Research

    Factors relating to the mental health of women who were pregnant at the time of the Great East Japan earthquake: analysis from month 10 to month 48 after the earthquake

    The Great East Japan Earthquake occurred at 2:46 p.m. on March 11, 2011. The epicenter was off the coast of Miyagi prefecture, and the magnitude of the earthquake was 9.0 with a maximum seismic intensity of 7....

    Kineko Sato, Maki Oikawa, Mai Hiwatashi, Mari Sato and Nobuko Oyamada

    BioPsychoSocial Medicine 2016 10:22

    Published on: 27 June 2016

  13. Research

    Factors associated with caregiving burden and mental health conditions in caregivers of patients with anorexia nervosa in Japan

    There are no studies about the caregiving burdens in families of patients with eating disorders in Japan, and only limited studies on the role of caregivers’ stress coping, social support, and mental health. T...

    Chisato Ohara, Gen Komaki, Zentaro Yamagata, Mari Hotta, Toshiko Kamo and Tetuya Ando

    BioPsychoSocial Medicine 2016 10:21

    Published on: 22 June 2016

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