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Table 4 Frequency of drug related adverse effects among patients in each group

From: A randomized, double-blind, placebo-controlled study to assess efficacy of mirtazapine for the treatment of diarrhea predominant irritable bowel syndrome

Adverse effects

N (%)

Group

P- value

Mirtazapine (N = 34)

Placebo (N = 33)

Drowsiness

12 (35.3%)

3 (9.1%)

0.01

Dizziness

6 (17.6%)

2 (6.1%)

0.25

Nausea

5 (14.7%)

2 (6.1%)

0.43

Dry mouth

9 (26.5%)

2 (6.1%)

0.04

Fatigue

10 (29.4%)

2 (6.1%)

0.02

Headache

4 (11.8%)

1 (3.0%)

0.36

Increased appetite

11 (32.4%)

2 (6.1%)

0.01

Weight gain

8 (23.5%)

1 (3.0%)

0.03