Factors affecting the dental erosion severity of patients with eating disorders
© Otsu et al.; licensee BioMed Central Ltd. 2014
Received: 18 June 2014
Accepted: 12 November 2014
Published: 19 November 2014
Intraoral disease is a common occurrence in patients with eating disorders, particularly dental erosion, which frequently becomes severe and may hinder daily life. The severity varies from patient to patient. Understanding the underlying mechanisms may help prevent dental erosion in these patients. Accordingly, we investigated the relationship between the severity of erosion and the behavior of patients with eating disorders, with a focus on daily diet and vomiting behavior.
A total 71 female eating disorder outpatients from the Clinical Center of Psychosomatic Dentistry of Nippon Dental University Hospital and the Psychosomatic Internal Medicine Department of Kudanzaka Hospital or who were hospitalized at Hasegawa Hospital were enrolled. Dental erosion severity and location were determined by oral examination. Patients who induced vomiting were queried on their behavior during vomiting and on routine diet habits. Patients with dental erosion were further divided into mild and severe groups based on the lesion severity and the groups compared.
Dental erosion was observed in 43 of 50 subjects who induced vomiting. Dental erosion was most frequent on the palatal side of the anterior maxillary teeth, occurring in 81.3% of the subjects. There were significant differences observed between the mild and severe groups according to post-vomiting oral hygiene. Significantly more subjects in the mild group consumed large amounts of water before vomiting, and significantly more subjects in the severe group routinely consumed carbonated beverages or sweetened food.
While self-induced vomiting is the main cause of dental erosion in eating disorder patients, the erosion severity may be affected by behavior when inducing vomiting or by routine consumption of certain foods and beverages. Addressing these factors may help prevent severe dental erosion in patients who chronically induce vomiting.
KeywordsEating disorders Dentistry Vomiting/PX Vomiting/CO Tooth erosion
Patients with eating disorders are more likely to demonstrate high levels of dental fear compared to other dental patients . Because of the presence of dental fear, potential nutritional deficiencies, and exposure to stomach acids from frequent vomiting, eating disorder patients may have numerous dental caries and intraoral diseases such as salivary gland swelling and dental erosion [2, 3]. Dental erosion in particular is often observed in patients with eating disorders, with some patients requiring complex restorative treatment for this condition [4–7].
Generally, dental erosion is a disease that affects people who are directly or indirectly exposed to hydrochloric, sulfuric, and other acids through their occupations . Recently, multiple studies have reported dental erosion due to overconsumption of carbonated beverages or citrus fruit [9, 10]. However, because these types of dental erosion usually progress gradually, patients usually do not experience symptoms such as pain induced by cold fluids, and even when symptoms do occur, the pain is minimal .
In contrast, dental erosion may progress quickly in eating disorder patients and interrupt daily life due to cold-induced pain or marked aesthetic damage [5, 11]. However, the severity of dental erosion varies among eating disorder patients and is not associated with the eating disorder’s duration [3, 5]. Instead, other factors are presumed be involved in the progression of dental erosion; determining these factors may help prevent severe damage.
Accordingly, we investigated the relation between the severity of dental erosion and the vomiting behavior and regular dietary habits of patients with eating disorders.
A total of 71 female eating disorder patients (aged 17–47 years, mean 31.1 years), including outpatients at the Clinical Center of Psychosomatic Dentistry of Nippon Dental University Hospital, the Psychosomatic Internal Medicine Department of Kudanzaka Hospital, and inpatients at Hasegawa Hospital, were enrolled. A physician who specializes in psychosomatic medicine or a psychiatrist examined the subjects to exclude physical illnesses and other mental disorders. An eating disorder was diagnosed according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition, text revision (DSM-IV-TR) . The duration of the eating disorder ranged from 1 to 26 years (mean 11.7 years). Anorexia Nervosa (AN) was diagnosed in 35 patients (Restricting type = 11, Binge-Eating/Purging type = 24), Bulimia Nervosa (BN) in 27 (Purging type = 21, Nonpurging type = 6), Eating Disorder Not Otherwise Specified in 3, and unclear diagnosis in six patients. Patients with AN or BN who binge ate and purged through the use of laxatives only were not included in the study. Based on self-induced vomiting behavior, patients were further classified into vomiting (n = 50) and non-vomiting (n = 21) groups.
All patients received an oral and written study explanation, and provided written consent to participate. This study was approved by the ethics review committees of the School of Life Dentistry of Nippon Dental University, Nippon Dental University Hospital, Kudanzaka Hospital, and Hasegawa Hospital.
The 50 vomiting group subjects were assigned to one of two subgroups based on dental erosion severity. Subjects without dental erosion and those with erosion only involving the enamel (E1, E2) were placed into the mild group (n = 24). Subjects with erosion reaching the dentin with or without tooth loss (E3, E4) were placed in the severe group (n = 26).
Subjects were queried on their habits before and after vomiting through a standardized interview with the dentists (MO and YI). The interview included questions concerning water consumption to induce vomiting; post-vomiting oral hygiene; and regular dietary habits, such as consumption of acidic foods and beverages, citrus fruit, and sugar-sweetened foods such as candy or gum.
Dental erosion frequency was compared between the vomiting and non-vomiting groups using the χ2 test. The mild and severe vomiting subgroups were compared using a t-test according to age and eating disorder duration, and a χ2 test for vomiting behavior and dietary habits.
Self-induced vomiting and dental erosion frequency
Dental erosion severity and incidence by location
Dental erosion severity, patient age, and disease duration
Patient age and eating disorder duration
Mild group (n =24)
Severe group (n =26)
Eating disorder duration (years)
Dental erosion severity and behavior before and after vomiting
Dental erosion severity and routine dietary habits
Several epidemiological studies have investigated the prevalence of dental erosion. In the adult population, prevalence data ranged between 4% and 100% . However, the methods and indices applied vary considerably, and this may limit the comparability of the prevalence data . A recent study reported that dental erosion was observed in 8.8% of a healthy control group, and 45.0% of an eating disorder group . In the present study, dental erosion was not observed in the non-vomiting group, while erosion was found in more than 80% of the vomiting group. This suggests that self-induced vomiting can cause dental erosion in patients with eating disorders. However, most notably, dental erosion was not observed in seven subjects in the vomiting group. This finding shows that vomiting is not always accompanied by dental erosion. Determining the protective mechanism underlying this finding could help preserve the teeth of patients with eating disorders, even if habitual self-induced vomiting cannot be stopped.
This study showed that dental erosion occurs most frequently on the palatal margin of the maxillary teeth as well as on the mandibular molar occlusal surfaces, where it is particularly severe. This is consistent with past studies characterizing endogenous dental erosion . As vomitus passes through the oral cavity, dental erosion targets surfaces unprotected by the tongue, buccal mucosa, or lips—surfaces experiencing direct vomitus contact. In addition, the eroded dentin on occlusal surfaces may be further subject to damage during mastication. These characteristic lesions may help dentists recognize endogenous dental erosion and to consider the possibility of an eating disorder. Frequently, the dentist is the first health care provider to find the clinical symptoms of an eating disorder . This may provide an opportunity to identify eating disorder patients who are not receiving medical attention. Thus, it is important for dentists to accurately recognize the pattern of dental erosion associated with eating disorders.
Dental erosion was less common in areas protected from direct acid exposure by the tongue and other structures. Using a device, such as a mouth guard, during vomiting could similarly suppress dental erosion . However, this intervention could also be interpreted as condoning the act of vomiting and warrants full debate.
Dental erosion severity did not correlate with the eating disorder duration or patient age. However, it is generally thought that acid exposure for longer periods and with more frequency increases the severity of tooth erosion. The subjects were not followed long-term but only underwent a one-time cross-sectional survey; therefore, the relationship between erosion severity and vomiting frequency and disease duration requires further study.
A large proportion of subjects in the mild group consumed water before inducing vomiting. Drinking water immediately before vomiting is thought to dilute the gastric contents and neutralize the vomitus acidity, thereby reducing dental erosion severity. In addition, diluted vomitus flows more easily, which may decrease residual vomitus in the mouth. The impact of significant pre-vomiting water consumption on the stomach, esophagus, and other organs warrants investigation from an internal medicine perspective. Our results suggest that this behavior can effectively protect the teeth from acid.
This study also showed that tooth brushing immediately after vomiting is harmful, a finding consistent with past studies showing that brushing after vomiting or eating acidic foods etches the acid onto tooth surfaces . In addition, brushing immediately after vomiting can remove the superficial tooth surface down to the decalcified layer, which can remineralize. A recent study has shown that approximately 83% of subjects who brushed their teeth following vomiting episodes suffered from dental erosion compared with subjects who only rinsed their mouth or did nothing . Therefore, to avoid worsening dental erosion, post-vomiting oral hygiene should comprise thorough oral rinsing with water or other liquids to neutralize acid in the oral cavity , waiting to allow remineralization, and careful tooth brushing.
Excessive consumption of acidic foods is believed to promote dental erosion [20, 21]. The critical pH of surface enamel is approximately 5.5, and approximately 6.7 in the exposed dentin. Generally, carbonated beverages and citrus fruit have a pH of approximately 3.0, more than capable of dissolving the tooth. Therefore, regular consumption of these products may cause chronic oral acidity, which may exacerbate dental erosion caused by vomiting. In addition, oral bacteria including Streptococcus mutans metabolize consumed sugars and produce lactic acid and other acids, generating oral acidity and promoting dental erosion. However, even in oral acidity caused by consuming acidic or sweetened foods, the teeth will remineralize after a certain period. Thus, if the oral cavity pH can be neutralized before tooth remineralization begins, dental erosion can be minimized, even if these food products are consumed.
For eating disorder patients, sugar consumption is often an important source of calories, and prohibiting these patients from consuming sweetened foods risks morbidity or fatality . As such, the progression of dental erosion should be slowed by changing how patients consume sweetened foods or by modifying behaviors after consumption, such as avoiding continuous consumption or rinsing the mouth afterwards.
Self-induced vomiting is the main cause of dental erosion in patients with eating disorders. Erosion occurs most frequently on the palatal side of the maxillary teeth and the mandibular molar occlusal surfaces, which come into direct contact with vomitus and gastric acid. Many patients exhibit severe erosion of the molars. Disease duration and patient age did not correlate with erosion severity.
This study also revealed that water consumption prior to vomiting and oral rinsing afterwards may help prevent erosion from progressing from mild to severe. Conversely, tooth brushing after vomiting had a detrimental effect. Not surprisingly, regular consumption of acidic or sweetened foods was associated with progression to severe erosion. Addressing these factors could help prevent the progression of dental erosion in patients who chronically induce vomiting.
This study was partly supported by the JSPS KAKENHI Grant (Number 25463266).
- Sirin Y, Yucel B, Firat D, Husseinova-Sen S: Assessment of dental fear and anxiety levels in eating disorder patients undergoing minor oral surgery. J Oral Maxillofac Surg. 2011, 69: 2078-2085. 10.1016/j.joms.2010.12.050.View ArticlePubMedGoogle Scholar
- Aranha AC, Eduardo Cde P, Cordás TA: Eating disorders. Part I: psychiatric diagnosis and dental implications. J Contemp Dent Pract. 2008, 9: 73-81.PubMedGoogle Scholar
- Willumsen T, Graugaard PK: Dental fear, regularity of dental attendance and subjective evaluation of dental erosion in women with eating disorders. Eur J Oral Sci. 2005, 113: 297-302. 10.1111/j.1600-0722.2005.00227.x.View ArticlePubMedGoogle Scholar
- Hermont AP, Pordeus IA, Paiva SM, Abreu MH, Auad SM: Eating disorder risk behavior and dental implications among adolescents. Int J Eat Disord. 2013, 46: 677-683. 10.1002/eat.22132.View ArticlePubMedGoogle Scholar
- Otsu M, Suzuki A, Hasegawa I, Miyauchi M, Karibe H, Okada T, Ishii T, Yamaoka M, Ichijyo T, Sato T: Dental problems in patients with eating disorder accompanied by self-induced vomiting –Oral environment. Jpn J Psychosom Med. 2006, 46: 960-968.Google Scholar
- Inoue H, Matsuzaka T, Suzuki K, Ootsuru H, Takagi S, Nagatani T, Nagatani N, Nishimura Y: Study of caries prevalence in those with eating disorders. Jpn J IRYOU. 2003, 57: 100-107.Google Scholar
- Otsu M, Hamura A, Ishikawa Y, Yamaoka M, Ichijyo T, Ishii T, Okada T, Karibe H, Sato T: Dental problems of patients with eating disorder accompanied by self-induced vomiting: DMFT, reasons for consultation. Jpn J Psychosom Med. 2011, 51: 329-335.Google Scholar
- Japanese Society for Oral Health industrial hygiene section: Dental Erosion and Industrial Health Management. 1985, Tokyo: Oral Health Association of Japan, 13-28.Google Scholar
- Cronin RJ, Cagna DR: Causes of severe tooth wear. Jpn Dental Outlook. 2003, 101: 254-265.Google Scholar
- O’Sullivan E, Milosevic A: UK National Clinical Guidelines in Paediatric Dentistry: diagnosis, prevention and management of dental erosion. Int J Paediatr Dent. 2008, 18: 29-38.View ArticlePubMedGoogle Scholar
- Otsu M, Hamura A, Miyauchi M, Okada T, Karibe H, Ishii T, Yamaoka M, Ichijyo T, Sato T: Efficiency of a mouth guard to prevent a toothache (cold-water pain) in a patient with eating disorder accompanied by self-induced vomiting. Jpn J Psychosom Med. 2010, 50: 139-145.Google Scholar
- American Psychiatric Association: Eating Disorders. In Diagnostic and Statistical Manual of Mental Disorders, Text Revision (DSM-IV-TR). 4th edition. Washington, DC: American Psychiatric Association; 2000:583–595.Google Scholar
- Jaeggi T, Lussi A: Prevalence, incidence and distribution of erosion. Monogr Oral Sci. 2014, 25: 55-73.View ArticlePubMedGoogle Scholar
- Schlueter N, Jaeggi T, Lussi A: Is dental erosion really a problem?. Adv Dent Res. 2012, 24: 68-71. 10.1177/0022034512449836.View ArticlePubMedGoogle Scholar
- Smith BGN, Knight JK: A comparison of patterns of tooth wear with aetiological factors. Br Dent J. 1984, 157: 16-19. 10.1038/sj.bdj.4805401.View ArticlePubMedGoogle Scholar
- Aranha AC, Eduardo Cde P, Cordás TA: Eating disorders part II: clinical strategies for dental treatment. J Contemp Dent Pract. 2008, 9: 89-96.PubMedGoogle Scholar
- Meurman JH, ten Cate JM: Pathogenesis and modifying factors of dental erosion. Eur J Oral Sci. 1996, 104: 199-206. 10.1111/j.1600-0722.1996.tb00068.x.View ArticlePubMedGoogle Scholar
- Hamasha AA, Zawaideh FI, Al-Hadithy RT: Risk indicators associated with dental erosion among Jordanian school children aged 12-14 years of age. Int J Paediatr Dent. 2014, 24: 56-68. 10.1111/ipd.12026.View ArticlePubMedGoogle Scholar
- Messias DC, Turssi CP, Hara AT, Serra MC: Sodium bicarbonate solution as an anti-erosive agent against simulated endogenous erosion. Eur J Oral Sci. 2010, 118: 385-388. 10.1111/j.1600-0722.2010.00749.x.View ArticlePubMedGoogle Scholar
- Lussi A, Jaeggi T, Zero D: The role of diet in the aetiology of dental erosion. Caries Res. 2004, 38: 34-44.View ArticlePubMedGoogle Scholar
- Wang X, Lussi A: Assessment and management of dental erosion. Dent Clin North Am. 2010, 54: 565-578. 10.1016/j.cden.2010.03.003.View ArticlePubMedGoogle Scholar
- Crow SJ, Peterson CB, Swanson SA, Raymond NC, Specker S, Eckert ED, Mitchell JE: Increased mortality in bulimia nervosa and other eating disorders. Am J Psychiatry. 2009, 166: 1342-1346. 10.1176/appi.ajp.2009.09020247.View ArticlePubMedGoogle Scholar
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