Table 4 Change in IBS symptom severity score (FAS)
IBS symptom | Visit | Na | Change in IBS symptom severity score | 95% CI of mean | Paired t-tests | ||||
|---|---|---|---|---|---|---|---|---|---|
Mean | SD | Minimum | Median | Maximum | |||||
Abdominal pain or abdominal discomfort | Week 2 | 67 | -0.53 | 0.53 | -1.9 | -0.60 | 0.9 | -0.66, -0.41 | p < 0.001 |
Week 4 | 67 | -0.57 | 0.70 | -2.6 | -0.60 | 1.4 | -0.73, -0.40 | p < 0.001 | |
Abdominal distension | Week 2 | 62 | -0.50 | 0.62 | -2.3 | -0.40 | 0.5 | -0.65, -0.34 | p < 0.001 |
Week 4 | 62 | -0.55 | 0.79 | -2.3 | -0.50 | 1.3 | -0.74, -0.35 | p < 0.001 | |
Borborygmi | Week 2 | 58 | -0.17 | 0.47 | -1.9 | -0.10 | 0.7 | -0.29, -0.05 | p = 0.007 |
Week 4 | 58 | -0.24 | 0.58 | -1.9 | -0.20 | 1.7 | -0.39, -0.09 | p = 0.002 | |
Flatulence | Week 2 | 55 | -0.27 | 0.57 | -1.9 | -0.10 | 0.9 | -0.42, -0.12 | p < 0.001 |
Week 4 | 55 | -0.39 | 0.76 | -2.4 | -0.30 | 1.7 | -0.60, -0.19 | p < 0.001 | |
Sensation of incomplete defecations | Week 2 | 65 | -0.26 | 0.58 | -2.3 | -0.20 | 1.0 | -0.39, -0.12 | p < 0.001 |
Week 4 | 65 | -0.39 | 0.60 | -2.3 | -0.30 | 0.6 | -0.53, -0.24 | p < 0.001 | |
Defecation urgency | Week 2 | 58 | -0.21 | 0.45 | -1.7 | -0.10 | 1.0 | -0.32, -0.10 | p < 0.001 |
Week 4 | 58 | -0.27 | 0.53 | -2.0 | -0.10 | 1.0 | -0.40, -0.13 | p < 0.001 | |
Straining at stool | Week 2 | 59 | -0.24 | 0.57 | -1.9 | -0.30 | 1.0 | -0.38, -0.09 | p = 0.002 |
Week 4 | 59 | -0.43 | 0.58 | -2.3 | -0.40 | 0.6 | -0.57, -0.28 | p < 0.001 | |
Belching | Week 2 | 36 | -0.03 | 0.49 | -1.3 | 0.00 | 1.0 | -0.19, 0.13 | p = 0.737 |
Week 4 | 36 | -0.19 | 0.59 | -1.8 | -0.05 | 1.4 | -0.38, 0.01 | p = 0.065 | |
Nausea | Week 2 | 26 | -0.12 | 0.50 | -1.8 | -0.05 | 0.9 | -0.31, 0.08 | p = 0.231 |
Week 4 | 26 | -0.21 | 0.65 | -2.4 | -0.10 | 1.4 | -0.47, 0.05 | p = 0.109 | |
Heartburn | Week 2 | 38 | -0.13 | 0.55 | -1.8 | -0.10 | 1.1 | -0.31, 0.05 | p = 0.151 |
Week 4 | 38 | -0.23 | 0.65 | -2.3 | -0.10 | 1.3 | -0.44, -0.02 | p = 0.033 | |