Atypical social cognition processing in bulimia nervosa: an fMRI study of patients thinking of others’ mental states

Table 1 Results of the demographic and clinical measures of patients and healthy women

	BN		HW		p-value
	Mean	SD	Mean	SD	p-value
Age (years)	26.50	6.79	26.64	7.03	0.948
BMI (kg/m²)	19.99	2.02	20.70	1.80	0.228
Duration of illness (years)	5.04	4.97
IQ	96.69	2.02	99.07	14.55	0.210
Education (years)	14.36	1.85	14.59	1.59	0.664
BITE-SAS	22.59	4.17	5.73	4.21	< 0.001
BITE-SS	11.00	4.98	1.55	1.06	< 0.001
EDE-Q total	3.81	1.32	1.14	0.74	< 0.001
PHQ-9	11.55	5.39	4.36	2.95	< 0.001
GAD-7	7.82	5.11	3.82	2.95	0.003
RMET(original; 36 items)	22.14	3.55	22.55	2.97	0.689
RMET(fMRI; 16 items)	9.14	1.46	8.50	1.82	0.207
Response time of social cognition (ms)	3756.97	658.99	3744.77	718.79	0.656
Response time of gender detection (ms)	1681.48	377.08	1629.11	387.84	0.954
Comorbidities (n)
Major depressive disorder	5
Medication (n)
SSRIs	3

BN; bulimia nervosa, HW; healthy women, BITE-SAS; the Symptom Assessment Scale of Bulimic Inventory Test, Edinburgh (30), BITE-SS; the Severity Scale of Bulimic Inventory Test, Edinburgh (30), EDE-Q; Eating Disorder Examination Questionnaire (29), PHQ-9; Patient Health Questionnaire - 9 (37), GAD-7; Generalized Anxiety Disorder -7 (38), RMET(fMRI); 16 selected items from the Reading the Mind in the Eyes Test (19) for the fMRI task. RMET(original); The Reading the Mind in the Eyes Test Japanese version on paper. SSRIs; selective serotonin reuptake inhibitors, Student’s t-test: age, BMI, IQ, education, BITE-SAS, RMET (fMRI), RMET (original), and Response time. Welch’s t-test: BITE-SS, EDE-Q total, PHQ-9, and GAD-7. The statistical significance was considered at the 5% level for all variables

ISSN: 1751-0759