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Table 4 Multiple linear regression analysis for QOL T-scores based on physical and psychosocial factors

From: Quality of life and physical/psychosocial factors in children and adolescents with orthostatic intolerance

  

Physical

Emotional

Self-esteem

Family

Friends

School

Total

n

T-score

β (95%CI)a

T-score

β (95%CI)a

T-score

β (95%CI)a

T-score

β (95%CI)a

T-score

β (95%CI)a

T-score

β (95%CI)a

T-score

β (95%CI)a

Disease factor

 Severity of OI

Mild

62

39.2

 

45.0

 

42.9

 

51.3

 

44.1

 

44.6

 

41.5

 

Severe

33

36.5

-0.7(-3.8, 2.4)

42.7

-0.7(-3.4, 2.0)

41.1

-0.8(-3.0, 1.4)

51.8

0.7(-1.5, 2.9)

38.6

-3.0(-6.1, 0.2)

45.6

-0.6(-3.2, 2.0)

40.5

-0.8(-3.5, 2.0)

 Experiences already diagnosed with OI

No

52

41.0

 

41.9

 

41.8

 

49.3

 

41.7

 

44.5

 

39.8

 

Yes

43

35.0

-2.9(-5.8, -0.1)*

46.9

2.0(-0.6, 4.6)

42.9

0.4(-1.7, 2.5)

54.1

1.9(-0.2, 4.0)

42.5

0.2(-3.0, 3.3)

45.6

0.1(-2.5, 2.6)

43.0

1.1(-1.6, 3.8)

Family factor

 Number of parents living with children

two parents

74

39.5

 

44.2

 

42.5

 

52.3

 

42.3

 

46.2

 

41.8

 

a single parent

21

33.8

-2.8(-6.2, 0.7)

43.9

0.5(-2.7, 3.7)

41.6

-0.2(-2.7, 2.3)

48.5

-1.4(-3.9, 1.1)

41.3

-0.2(-3.9, 3.6)

41.1

-2.4(-5.2, 0.5)

38.9

-1.2(-4.3, 1.9)

 Family with psychiatric disorders

No

78

37.5

 

45.0

 

42.4

 

52.5

 

41.1

 

44.7

 

41.7

 

Yes

17

41.4

1.3(-2.4, 5.0)

40.4

2.0(-5.5, 1.2)

41.6

-0.4(-3.1, 2.2)

46.9

-2.8(-5.4, -0.2)*

41.8

-0.3(-4.3, 3.7)

46.5

1.0(-2.3, 4.3)

38.7

-1.7(-5.2, 1.7)

School factor

 Academic grade

Good

72

37.9

 

44.3

 

43.0

 

52.4

 

42.8

 

46.2

 

42.0

 

Not good

23

39.2

-0.4(-3.9, 3.2)

43.5

-0.1(-3.3, 3.1)

40.0

-1.6(-4.0, 0.8)

48.6

-1.8(-4.3, 0.7)

39.9

-1.6(-5.3, 2.1)

41.1

-1.3(-4.3, 1.7)

38.0

-1.5(-4.8, 1.9)

 Relationship with school

Good

86

38.6

 

44.5

 

42.6

 

51.6

 

44.1

 

45.1

 

41.9

 

Not good

9

34.2

-3.6(-8.5, 1.3)

40.6

-3.0(-7.4, 1.4)

39.1

-2.2(-5.7, 1.3)

50.5

-1.6(-5.1, 1.9)

24.7

-10.7(-15.3, -6.1)**

43.3

-0.3(-5.0, 4.3)

33.0

-5.0(-9.8, -0.4)*

 School nonattendance

No

31

42.3

 

46.2

 

43.5

 

51.5

 

47.2

 

46.3

 

44.6

 

Yes

64

36.2

-3.8(-6.9, -0.7)*

43.1

-2.9(-5.7, -0.1)*

41.7

-1.2(-3.4, 1.1)

51.6

-0.9(-3.2, 1.4)

39.5

-3.7(-7.0, -0.4)*

44.2

-0.2(-2.8, 2.4)

39.0

-3.2(-5.8, -0.5)*

Social factor

 Social problem

No

73

39.2

 

45.4

 

42.7

 

52.1

 

43.7

 

46.0

 

41.9

 

Yes

22

35.2

-2.4(-5.8, 1.1)

40.1

-3.2(-6.3, -0.2)*

40.8

-0.9(-3.4, 1.5)

49.6

-1.5(-4.0, 1.0)

36.3

-2.9(-6.7, 0.8)

41.4

-0.9(-3.9, 2.0)

38.4

-1.4(-4.6, 1.9)

 Activities outside of school

No

44

38.0

 

43.7

 

42.1

 

50.0

 

41.0

 

43.8

 

40.4

 

Yes

51

38.4

0.7(-2.2, 3.6)

44.6

0.1(-2.5, 2.8)

42.4

0.1(-1.9, 2.2)

52.9

1.3(-0.8, 3.3)

43.0

1.1(-2.0, 4.2)

46.0

0.5(-2.0, 3.0)

41.8

0.5(-2.2, 3.1)

  1. Significant difference, *p<0.05, **p<0.01
  2. Missing value are included : of 95 patients, 1 in physical, 2 in emotional, 1 in self-esteem, 2 in family, 8 in friends, 16 in school, and 21 in total are missing.
  3. QOL Quality of life, OI Orthostatic intolerance
  4. aAdjusted for sex, school levels (elementary school or junior high school) and presence of comorbidities