Table 1 Three-way ANOVA results of the elevated plus-maze

(A) Time spent open arm

 Sex

1

12.073

0.001**

 MS

1

11.228

0.001**

 TNBS

1

1.106

0.296

 Sex × MS

1

4.772

0.031*

 Sex × TNBS

1

0.673

0.414

 MS × TNBS

1

0.052

0.821

 Sex × MS × TNBS

1

0.34

0.561

 Residuals

102

(B)% Time spent open arm

 Sex

1

12.044

0.001**

 MS

1

11.212

0.001**

 TNBS

1

1.108

0.295

 Sex × MS

1

4.782

0.03*

 Sex × TNBS

1

0.669

0.415

 MS × TNBS

1

0.052

0.82

 Sex × MS × TNBS

1

0.337

0.563

 Residuals

102

(C) % Open arm enties

 Sex

1

10.204

0.002*

 MS

1

7.751

0.006*

 TNBS

1

0.815

0.369

 Sex × MS

1

6.204

0.014*

 Sex × TNBS

1

2.237

0.138

 MS × TNBS

1

0.041

0.84

 Sex × MS × TNBS

1

0.026

0.873

 Residuals

102

(D) Time spent closed arm

1

 Sex

1

19.356

0.0001***

 MS

1

11.39

0.001**

 TNBS

1

1.759

0.188

 Sex × MS

1

4.178

0.044*

 Sex × TNBS

1

0.075

0.785

 MS × TNBS

1

0.072

0.789

 Sex × MS × TNBS

1

0.631

0.429

 Residuals

102

(E) Total travel distance

 Sex

1

8.243

0.005*

 MS

1

4.379

0.038*

 TNBS

1

1.089

0.298

 Sex × MS

1

0.677

0.412

 Sex × TNBS

1

3.180

0.077

 MS × TNBS

1

0.901

0.344

 Sex × MS × TNBS

1

2.867

0.092

 Residuals

102