Clinical effects of wasabi extract containing 6-MSITC on myalgic encephalomyelitis/chronic fatigue syndrome: an open-label trial

Table 7 Changes in psychological indices after 6-MSITC treatment

	Descriptive	Pre	Post	Δ	P	ES
POMS-2	Anger	48.8 ± 11.0	48.0 ± 7.8	-0.8 ± 8.6	0.726	0.09
	Confusion	57.7 ± 10.9	54.8 ± 8.3	-2.9 ± 9.6	0.258	0.3
	Depression	52.3 ± 11.6	51.9 ± 11.2	-0.47 ± 5.0	0.726	0.09
	Fatigue	53.0 ± 8.7	54.4 ± 10.5	1.3 ± 6.7	0.451	-0.2
	Tension	52.3 ± 10.2	50.7 ± 10.3	-1.6 ± 6.0	0.318	0.27
	Vigor	46.9 ± 8.0	50.0 ± 10.7	3.1 ± 5.4	0.045	-0.57
	Friendship	48.7 ± 9.3	52.7 ± 12	4 ± 7.3	0.056	-0.54
	TMD	53.7 ± 9.9	52.1 ± 10.8	-1.7 ± 5.5	0.257	0.3
HADS	Anxiety	7.1 ± 4.2	6.3 ± 4.1	-0.8 ± 2.4	0.222	0.33
HADS	Depression	9.0 ± 3.9	7.1 ± 4.6	-1.9 ± 4	0.091	0.47

Δ: differences between scores before and after treatment (subtraction of Pre from Post), HADS Hospital Anxiety and Depression Scale. ES: effect sizes were calculated using the Cohen’s d. P: p values were analyzed using a parametric paired Student’s t-test. POMS-2 Profile of Mood States-2, TMD Total mood disturbance; (n = 15)

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