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Table 1 Patient characteristics (N = 113)

From: Association between polypharmacy and the persistence of delirium: a retrospective cohort study

 

Delirium

(n = 49)

No delirium

(n = 64)

P-value

Age (years), mean (SD)

80.76 (11.90)

81.81 (8.25)

0.60

Male sex, n (%)

28 (57)

34 (53)

0.81*

Charlson comorbidity index, mean (SD)

3.14 (2.02)

2.92 (2.35)

0.59

Karnofsky Performance Status, mean (SD)

39.59 (20.61)

48.44 (25.02)

0.04

Number of drugs, mean (SD)

7.04 (3.26)

6.14 (3.95)

0.19

Number of drugs with psychotropics, mean (SD)

10.02 (3.78)

8.66 (4.11)

0.07

Psychotropics use, n (%)

 Antipsychotics

33 (67)

39 (61)

0.61*

 Benzodiazepine or Z-drugs

12 (24)

13 (20)

0.76*

 Ramelteon or suvorexant

41 (84)

55 (86)

0.95*

 Antidepressant

3 (6)

2 (3)

0.65

 Other drugs

19 (39)

18 (28)

0.32*

  1. Other drugs included anti-dementia drugs, valproic acid, Yokukansan
  2. *, Chi-squared test; , Fisher’s exact test; , Student’s t-test