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Table 2 Results from multivariate regression models in the Diast-CHF study group with HADS anxiety as the dependent variable

From: Higher galectin-3 levels are independently associated with lower anxiety in patients with risk factors for heart failure

  B 95% confidence interval β P value
Model 1: Total model p < 0.001, adjusted R2 = 0.115, F = 15.051
 Galectin-3 -2.493 -4.354;-0.632 -0.080 0.009
 Gender 0.605 0.128;1.082 0.081 0.013
 Age -0.054 -0.091;-0.018 -0.114 0.004
 BMI 0.055 -0.114;0.004 -0.071 0.066
 eGFR 0.008 -0.004;0.020 0.056 0.214
 LVEF 0.021 -0.009;0.050 0.043 0.173
 ASE grade 0.136 -0.219;0.490 0.024 0.453
 6-min walking distance 0.002 -0.001;0.004 0.059 0.127
 SF-36 physical functioning -0.057 -0.068;-0.045 -0.355 < 0.001
Model 2: Total model p < 0.001, adjusted R2 = 0.108, F = 9.483
 Galectin-3 -2.413 -4.422;-0.404 -0.077 0.019
 Gender 0.249 -0.323;0.821 0.033 0.394
 Age -0.053 -0.094;-0.013 -0.111 0.010
 BMI -0.034 -0.101;0.033 -0.043 0.318
 eGFR -0.002 -0.016;0.012 -0.013 0.809
 LVEF 0.007 -0.025;0.039 0.015 0.669
 ASE grade 0.200 -0.189;0.589 0.035 0.314
 6-min walking distance 0.002 -0.001;0.004 0.044 0.287
 SF-36 physical functioning -0.056 -0.069;-0.043 -0.345 < 0.001
 CT-proAVP -0.913 -1.776;0.050 -0.078 0.038
 NT-proBNP -0.286 -1.212;0.640 -0.034 0.545
 MR-proANP -0.843 -2.665;0.979 0.052 0.364
  1. Results from multivariate linear regression models with HADS anxiety scores as dependent variable and plasma galectin-3 as independent variable adjusted for gender, age, BMI body-mass index, eGFR estimated glomerular filtration rate, LVEF left ventricular ejection fraction, ASE grade American Society of Echocardiography, 6-min walking distance, SF-36 physical functioning and, optionally, CT-proAVP, and natriuretic peptides NT-proBNP and MR-proANP