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Table 2 Treatment as usual (TAU) differs in eight psychotherapeutic RCTs on coronary artery disease and outcome related to psychological symptoms and survival

From: The effects of usual Care in Psychosocial Intervention Trials of patients with coronary artery disease: a systematic review

 

Enhanced TAU

Outcome in TAU

Randomized Controlled Trial

Years in the study

No of personal examinations

Additional therapeutic activity

Reduction of psychological symptoms

Survival rate (%) at end of study

Estimated survival rate within 8 years1

RCPP [19]

4.5 y.

5 (3 cardiologic, 2 psycho logical)

33 group sessions à 90 min.

Type A behaviour: −9.8%; ES2: 0.72; 95%CI 0.89–0.56

92.8%

87.2

Jones and West [20]

1 y.

3

0

depression not specified for TAU

92.8%

42.4%1

M-HEART [21]

1 y.

3 (1 cardiological, 3 psychological)

0

BDI depression: - 9.5%; ES2: 0.1; 95%CI 0.26–0.07

94.6%

56.8%1

ENRICHD [22]

2.4 y.

5 (cardiolog.,psychological)

Active partnership Health booklet

BDI depression: −33%; ES2: 0.69; 95%CI 0.85–0.53

86.2%.

54.3%

CREATE [23]

0.25 y

2 (cardiolog.,psychological)

12 × 20 min clinical management

BDI: − 40.3% HAMD:-48%; ES2: 1.81; 95%CI 2.2–1.42

100% /

?

SWICHD [24]

7.1 y.

1(cardiolog, psychological; 2x questionnaires by letter)

0

depressive symptoms: −16.1%; ES3: 0.25; 95%CI 0.64–0.14

80.1% /

77.6%

SUPRIM [25]

7.8 y.

5 (cardiological, psychological)

0

Depression not reported

85.2% /

84.8%

SPIRR-CAD [26]

2 y.

5 (2x cardiologic, 5x psychological)

30 min information on risk factors

HADS-D − 13.4%; ES4:0.41 95%CI 0.65–0.18 remission on HADS-D 35.8%

96.8% /

87.2%

  1. 1 8 years survival rate was predicted using survival data of the individual study. Presented studies differ in time
  2. between 0,25 years and 7.8 years. Mortality is higher in the year after the event. So in studies with a one or two
  3. years follow up period the estimated value of 8 years survival may be higher.
  4. 2mean and standard deviation at baseline and follow up (RCCP:4.5 y.;M-Heart:1 y.; ENRICHD (depressed
  5. participants only): 6 months; CREATE:3 months)
  6. 3 mean and standard deviation at baseline and follow up (1–2 years), published by Koertge J et al. J Intern Med
  7. 2007;263:281–293
  8. 4LOCF ANCOVA mean and standard deviation at baseline and follow up (24 months)