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Table 7 Severity of the “most bothersome symptoms” in the surrogate Rome IV FBD and IBS-C subjects

From: Influence of the requirement for abdominal pain in the diagnosis of irritable bowel syndrome with constipation (IBS-C) under the Rome IV criteria using data from a large Japanese population-based internet survey

GI symptoms 0:Very mild 1:Mild 2:Moderate 3:Severe 4:Very Severe p-value
(Surrogate Rome IV FBD vs Surrogate Rome IV IBS-C)
Abdominal bloating       
 Surrogate Rome IV FBD subjects (n = 88) 0 4.5 28.4 52.3 14.8 n.s.
 Surrogate Rome IV IBS-C subjects (n = 33) 6.1 3.0 12.1 54.5 24.2  
Abdominal discomfort
 Surrogate Rome IV FBD subjects (n = 48) 2.1 6.3 41.7 33.3 16.7 n.s.
 Surrogate Rome IV IBS-C subjects (n = 27) 0 3.7 33.3 33.3 29.6  
Abdominal pain
 Surrogate Rome IV FBD subjects (n = N/A) N/A N/A N/A N/A N/A N/A
 Surrogate Rome IV IBS-C subjects (n = 17) 5.9 5.9 23.5 52.9 11.8  
  1. Data are expressed as rate (%)
  2. GI, gastrointestinal