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Table 6 Occurrence situations of the “most bothersome symptoms” in the surrogate Rome IV FBD and IBS-C subjects

From: Influence of the requirement for abdominal pain in the diagnosis of irritable bowel syndrome with constipation (IBS-C) under the Rome IV criteria using data from a large Japanese population-based internet survey

Situations/Symptoms Total
(Abdominal pain or discomfort in the last 3 months
≥ 1 day/week)
Not experiencing abdominal pain Experiencing abdominal pain
Surrogate Rome III IBS-C subjects Surrogate Rome IV FBD subjects Surrogate Rome IV IBS-C subjects
Abdominal bloating
(n = 121)
Abdominal discomfort
(n = 75)
Abdominal pain
(n = 17)
Abdominal bloating
(n = 88)
Abdominal discomfort
(n = 48)
Abdominal pain
(n = N/A)
Abdominal bloating
(n = 33)
Abdominal discomfort
(n = 27)
Abdominal pain
(n = 17)
On the way to work/school by bus or train 19.8 24.0 0 17.0 18.8 N/A 27.3 33.3 0
At work/school 31.4 36.0 23.5 31.8 27.1 N/A 30.3 51.9 23.5
During a conference presentation/an exam 5.0 12.0 5.9 6.8 4.2 N/A 0 25.9 5.9
After drinking alcohol 0.8 6.7 0 1.1 6.3 N/A 0 7.4 0
After drinking milk 3.3 5.3 11.8 3.4 2.1 N/A 3.0 11.1 11.8
After a meal 56.2 42.7 41.2 54.5 45.8 N/A 60.6 37.0 41.2
On a sightseeing trip 23.1 13.3 0 19.3 14.6 N/A 33.3 11.1 0
On a business trip 3.3 8.0 0 3.4 6.3 N/A 3.0 11.1 0
During time of stress 28.1 28.0 35.3 27.3 22.9 N/A 30.3 37.0 35.3
After taking medication 2.5 1.3 11.8 3.4 0 N/A 0 3.7 11.8
During menstruation (females only) 7.4 10.7 35.3 6.8 4.2 N/A 9.1 22.2 35.3
  1. Data are expressed as frequencies (%)