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Fig. 3 | BioPsychoSocial Medicine

Fig. 3

From: Neural correlates of body comparison and weight estimation in weight-recovered anorexia nervosa: a functional magnetic resonance imaging study

Fig. 3

Group-by-stimulus 2-way interactive effect on BOLD signals during the comparison task. a The cluster rendered on the sagittal brain section shows the group-by-stimulus 2-way ANOVA interactive effect for the comparison task on BOLD signals in the left pregenual anterior cingulate (pgACC; the maximum peak of the effect at the MNI coordinates: x = − 10, y = 36, z = − 2 mm; cluster size: k = 6 voxels; peak Z score = 4.30, p = 0.008, FWE corrected for multiple comparisons). The analysis was based on a region of interest (ROI) analysis, with small volume correction (SVC) within the left pregenual ACC (a 12-mm radius sphere centered on x = − 7, y = 34, z = 5). The left color bar indicates the F value of the rendered cluster. b The bar graph shows the parametric estimates from the ANOVA analysis of the BOLD signals in the left pgACC cluster in each group (recAN and control) for each stimulus type (underweight, healthy weight, and overweight). Post hoc t-tests showed significantly greater BOLD signals in patients with recAN than in controls. Error bars indicate standard error. * p < 0.05 (Bonferroni-corrected), ** p < 0.01 (Bonferroni-corrected).. MNI: Montreal Neurological Institute; BOLD: blood oxygen level dependent; FWE: family-wise error; recAN: recovered anorexia nervosa

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