Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study

Table 2 Hazard ratios for MACcE after CABG according to affective disorders, disorder clusters, and symptom dimensions

Model structure	N (%)^a	Hazard ratio^b	95 % CI lower	95 % CI upper	P
Model 1: Diagnostic Level - Disorders
Generalized Anxiety Disorder	16 (10.2)	2.79	1.00	7.80	.049
Major Depression	27 (17.1)	1.04	.40	2.67	.94
Panic Disorder	12 (10.8)	.36	.08	1.76	.21
Model 2: Theoretical Level - Disorder Clusters
Distress disorders^c	39 (24.7)	2.14	.92	4.95	.08
Fear disorders^d	21 (13.3)	.24	.05	1.20	.08
Model 3: Theoretical Level - Symptom Dimensions
MASQ General Negative Affect	19.1 ± 3.0	1.07	.89	1.30	.46
MASQ Anhedonia	16.5 ± 3.2	1.04	.85	1.26	.73
MASQ Anxious Arousal	22.8 ± 4.5	.94	.84	1.06	.30

CABG coronary artery bypass graft, CI confidence interval, HR hazard ratio, MACCE major adverse cardiovascular and cerebrovascular events, MASQ Mood and Anxiety Symptom Questionnaire
^aThe M ± SD is reported for MASQ General Negative Affect, Anhedonia and Anxious Arousal
^bHazard model adjusted for EuroSCORE, smoking, body mass index, hypertension, heart failure, peripheral vascular disease
^cMisery cluster comprised by major depression, dysthymia, generalized anxiety disorder and post-traumatic stress disorder
^dFear disorder cluster comprised by panic disorder, agoraphobia, social phobia

ISSN: 1751-0759