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Table 2 Hazard ratios for MACcE after CABG according to affective disorders, disorder clusters, and symptom dimensions

From: Depression, anxiety and major adverse cardiovascular and cerebrovascular events in patients following coronary artery bypass graft surgery: a five year longitudinal cohort study

Model structure N (%)a Hazard ratiob 95 % CI lower 95 % CI upper P
Model 1: Diagnostic Level - Disorders      
Generalized Anxiety Disorder 16 (10.2) 2.79 1.00 7.80 .049
Major Depression 27 (17.1) 1.04 .40 2.67 .94
Panic Disorder 12 (10.8) .36 .08 1.76 .21
Model 2: Theoretical Level - Disorder Clusters      
Distress disordersc 39 (24.7) 2.14 .92 4.95 .08
Fear disordersd 21 (13.3) .24 .05 1.20 .08
Model 3: Theoretical Level - Symptom Dimensions      
MASQ General Negative Affect 19.1 ± 3.0 1.07 .89 1.30 .46
MASQ Anhedonia 16.5 ± 3.2 1.04 .85 1.26 .73
MASQ Anxious Arousal 22.8 ± 4.5 .94 .84 1.06 .30
  1. CABG coronary artery bypass graft, CI confidence interval, HR hazard ratio, MACCE major adverse cardiovascular and cerebrovascular events, MASQ Mood and Anxiety Symptom Questionnaire
  2. aThe M ± SD is reported for MASQ General Negative Affect, Anhedonia and Anxious Arousal
  3. bHazard model adjusted for EuroSCORE, smoking, body mass index, hypertension, heart failure, peripheral vascular disease
  4. cMisery cluster comprised by major depression, dysthymia, generalized anxiety disorder and post-traumatic stress disorder
  5. dFear disorder cluster comprised by panic disorder, agoraphobia, social phobia
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