Table 2 Studies examining the effects of alexithymia on health outcomes with a prospective cohort design in clinicalpopulation

Adverse effect

Psychiatric inPT

4, 8-12W

Multimodal psychotherapy

Global severity Index and depression severity

480

Germany

24

Substance users

10+15W

Motivational intervention

Response to treatment

260

USA

25

Psychiatric outPT

12-21 W

Short-term psychotherapy

Psychiatric symptomatology

251

Canada

26

Hemodialysis outPT

5Y

Hemodialysis therapy

All cause mortality

230

Japan

27

Hemodialysis outPT

6M

Hemodialysis therapy

Depression deterioration

230

Japan

28

OutPT with possible

6Y

Pyschotherapy

Recovery from depression

121

Finland

29

Veterans with military sexual trauma.

7W

Specialized residential treatment

Symptom persistence

175

USA

30

Women taking elective surgical abortion

2M

Surgical abortion

Re-experience and avoidance

140

Netherlands

31

OutPT with functional gastrointestinal disorders

6M

Unspecified treatment

Response to treatment

112

Italy

32

PT taking implantable cardioverter defibrillator

2-5.5 Y

ICD placement

Posttraumatic stress

107

Switzerland

33

Eating disorder PT

3Y

Drug treatment and psychotherapy

PT’ compliance and types of treatments

102

France

34

Eating disorder PT

3Y

Unspecified treatment

Response to treatment

102

France

35

OutPT with major depression

1Y

Unspecified treatment

Response to treatment

86

Finland

36

PT with asthma

2Y

Unspecified treatment

Emargency room visits and QOL (SF-36)

76

Spain

37

OutPT with major depression

10W

Antidepressant

Reduction of depression severity

65

Turkey

38

PT with type 1 Diabetes

8W

Inpatient treatment

Decrease in HbA1c

64

Belgium

39

Alcohol abuser

15W

Inpatient treatment

Maintaining abstinent

46

France

40

PT with somatoform and anxiety disorder

2Y

Inpatient treatment

Symptom persistence

30

Austria

41

Beneficial effect

Cancer PT

6M

Multicomponent psychological intervention

Pain

104

Italy

42

PT taking in vitro fertilization

6M

In vitro fertilization

Delivery of a living infant

81

Greece

43

Colorectal cancer PT

3Y

Surgery

QOL (SF-36)

60

Italy

44

Ulcerative colotis PT

17M

Pelvic pouch surgery

Psychosocial adjustment

53

Sweden

45

Gynecologic PT

1M

Laparoscopy or laparotomy

QOL (SF-36)

40

Italy

46

No association

Psychiatric inPT

4, 8-12W

Psychodynamic group therapy

Global severity Index and depression severity

297

Germany

47

OutPT with unexplained physical symptom

6W

Unspecified treatment

Symptom persistence

127

Netherland

48

Pregnant women

1M

Unspecified

Depression development

149

Italy

49

PT with psoriasis

6M

Cognitive behavioral therapy

Response to treatment

80

UK

50

Obese outPT

8M

Behavioral program

Compliance and weight loss

68

Italy

51

InPT taking respiratory rehabilitation

4W

Respiratory rehabilitation

Functional recovery

60

Italy

52

Panic disorder PT

6M

CBT

Response to treatment

55

Switzerland

53

Psychiatric consultation outPT

1Y

Psychotherapy

PT’s compliance

54

Finland

54

OCD inPT

31-139 D

Multimodal CBT

Response to treatment

42

Germany

55

Bulmia nervosa PT

10W

Drug treatment

Symptom improvements

41

England

56

CFS outPT

18M

Unspecified treatment

Symptom improvements

40

Netherland

57

OutPT with psoriasis

3M

Delmatological treatment

Response to treatment

40

France

58

OCD inPT

6Y

Inpatient treatment

OCD deteriotion

34

Switzerland

59

Schizophrenia outPT

1Y

Appropriate treatment

Symptom improvements

29

Italy

60

Eating disorder inPT

1Y

Psychoeducation

Dietary restraint

19

Switzerland

61