Altered autonomic nervous system activity as a potential etiological factor of premenstrual syndrome and premenstrual dysphoric disorder

Table 1 Clinical characteristics of subjects in the follicular and late luteal phase

	Control group (n = 28)		PMS group (n = 23)		PMDD group (n = 11)
	Follicular	Luteal	Follicular	Luteal	Follicular	Luteal
Estrone (ng/ml Cr)	10.7 ± 1.0	19.4 ± 2.2**	10.9 ± 1.4	19.3 ± 2.5**	11.3 ± 2.8	21.7 ± 3.5*
Pregnanediol-3-glucuronide (μg/ml Cr)	0.4 ± 0.04	2.1 ± 0.19**	0.3 ± 0.04	2.2 ± 0.3**	0.8 ± 0.4	2.1 ± 0.4
Weight (kg)	54.7 ± 1.2	55.0 ± 1.3	55.9 ± 1.6	56.0 ± 1.6	51.8 ± 2.4	52.6 ± 2.4
Body Mass Index (kg/m²)	21.9 ± 0.5	22.0 ± 0.5	21.1 ± 0.5	21.2 ± 0.5	20.5 ± 0.9	20.8 ± 0.9

Cr: creatinine
Values are means ± SE. **p < 0.01; *p < 0.05 (follicular phase vs. late luteal phase)

ISSN: 1751-0759